Materiales
Materiales
Forsythiaside A Ameliorates Oxidative Damage Caused by Cerebral Ischemia Through the Nrf2/HO‐1 Signaling Pathway
04/03/2025 -
Forsythiaside A attenuates the oxidative stress induced by ischemic stroke by activating the Nrf2/HO‐1 signaling pathway to ameliorate neuronal injury and improve the neurological...
Protocatechuic Acid Alleviates Inflammation and Oxidative Stress in Acute Respiratory Distress Syndrome by Promoting Unconventional Prefoldin RPB5 Interactor 1‐Mediated Mitophagy
05/03/2025 -
A model proposing the mechanism. PCA ameliorates inflammation and oxidative stress in ARDS by promoting CBX4 expression and inducing URI1‐mediated mitophagy in pulmonary microvascular endothelial...
Fermentation-Mediated Enhancement of Safety, Thermal Stability, Bioaccessibility, and Health-Promoting Potential of Watermelon Peel Polyphenol Extract
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Abstract Fruit wastes contain significant levels of polyphenols with various health-related effects. However, polyphenols have several limitations that hinder their industrial...
One-Pot Synthesis and Characterization of Naringenin-Capped Silver Nanoparticles with Enhanced Biological Activities
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Abstract Flavonoids are known to possess biological effects like anti-inflammatory, antibacterial, antioxidant, and antidiabetic properties. Similarly, silver nanoparticles...
The Potent Antioxidant 3,5‐Dihydroxy‐4‐Methoxybenzyl Alcohol Reveals Anticancer Activity by Targeting Several Signaling Pathways in Bone Metastatic Human Breast Cancer MDA‐MB‐231 Cells
25/02/2025 -
DHMBA blocks cell proliferation upon EGF stimulation and suppresses growth and metastatic activity by regulating various signaling processes in human breast cancer cells. DHMBA may protect against...
The Molecular Mechanism of Resveratrol in the Treatment of Chronic Rhinosinusitis Through a Combination of Network Pharmacology and In Vitro Validation
25/02/2025 -
A combination of network pharmacology and in vitro validation was used to reveal the potential targets and molecular mechanisms of resveratrol for CRS treatment.ABSTRACTResveratrol (RES) is a...
Lab‐in‐Cell: A Covalent Photosensitizer Reverses Hypoxia and Evokes Ferroptosis and Pyroptosis for Enhanced Anti‐Tumor Immunity
23/02/2025 -
The covalent warhead alkynamide is incorporated into an aggregation‐induced emission photosensitizer, developing a redox systems‐targeting covalent photosensitizer MBTP‐PA. It is aimed at...
Phytochemical-Mediated Green Synthesis of Silver, Copper, and AgâCu Bimetallic Nanoparticles Using Peganum harmala Demonstrating Advanced Catalytic, Antioxidant, and Biomedical Applications
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Abstract This study explores the green synthesis of silver (Ag-NPs), copper (Cu-NPs), and silver-copper bimetallic nanoparticles (AgâCu Bimetallic NPs) using the leaf extract...
Elucidating the Secondary Metabolite Biosynthesis Networks in Underutilized Tree Bean (Parkia timoriana) Through Integrated Metabolomic and Transcriptomic Approaches
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Abstract The tree bean (Parkia timoriana (DC). Merr) is an underutilized legume and is abundantly found in Southeast Asia. It is valued for its nutritious pods and...
Assessment of Phytochemical Profile, Antioxidant, and Anticancer Activity Against Colon Cancer-HT-29: A Potent Therapeutic Medicinal Plant (Tarenna alpestris) in Megamalai Hills, Western Ghats, India
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Abstract Medicinal plants have long been recognized as a valuable source of human health due to their therapeutic potential in treating a variety of diseases. Tarenna...
Synthesis and characterization of new (Au, Ru, and Rh) ion complexes and evaluating their activity as anticancer and antioxidants
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Abstract Azo dye was used to prepare a new series of complexes with chlorides of rhodium (Rh+3), ruthenium (Ru+3), and corona (Au+3). The prepared materials were subjected to...
Therapeutic Scrutiny of Lentinus polychrous with Attention to Its Antioxidant, Antimicrobial, and Anticancer Attributes
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Abstract Mushrooms, being a source of therapeutically active compounds, are of great interest to researchers due to their historical usage in traditional therapies and the...
Imino and Thioureidic Derivatives as New Tools for Alzheimer's Disease: Preliminary Studies
16/01/2025 -
Among all tested molecules, octane‐1,8‐diyl‐bis‐S‐amidinothiourea dihydrobromide (4) showed a moderate antioxidant activity and the highest AChE inhibition activity. These results suggested...
Fabrication Techniques and Their Impact on the Properties of Microalgae‐Based Hybrid Biochemobrionic Materials
09/01/2025 -
A hybrid biochemobrionic material is developed by incorporating Chlorella vulgaris microalgae into the calcium–magnesium silicate–phosphate chemobrionic structure using two different methods. The...
Machine Learning‐Assisted High‐Throughput Screening of Nanozymes for Ulcerative Colitis
12/01/2025 -
A data‐driven design strategy is developed for UC therapeutic nanozymes. The optimal CT‐imageable oral UC therapeutic nanozyme SrDy2O4 is successfully discovered and the high‐dimensional...
Metformin Alleviates Doxorubicin-Induced Cardiotoxicity via Preserving Mitochondrial Dynamics Balance and Calcium Homeostasis
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Abstract Doxorubicin (DOX) is a commonly used chemotherapeutic medication for treating malignancies, although its cardiotoxicity limits its use. There is growing evidence that...
In Vitro Cytotoxic Potential and Integrated Network Pharmacology, Molecular Docking and Molecular Dynamic Approaches to Decipher the Mechanism of Gymnostachyum febrifugum Benth., in the Treatment of Breast Cancer
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Abstract Gymnostachyum febrifugum, a less-known ethnomedicinal plant from the Western Ghats of India, is used to treat various diseases and serves as an antioxidant and...
Phytochemical and Antioxidant Analysis of Bioactive Compound Extract from Nelumbo nucifera against Cancer Proteins: In Silico Spectroscopic Approach
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Abstract Nelumbo nucifera, an aquatic crop cultivated throughout Asian countries, belongs to the Nelumbonaceae family and has been widely used in traditional medicines...
Synergy of Hydrophilic Properties and Antibacterial Inhibition in Polyvinyl Alcohol Nanofibrous Mats Loaded With Croton Bonplandianum Baill Leaf Extract
06/01/2025 -
ABSTRACTThe antibacterial nanofibrous mat is crucial in biomedicine as it enhances infection control, expedites wound healing, and mitigates health hazards by decreasing antibiotic usage. A novel...
Eco-friendly Synthesis of Iron Oxide Nanoparticles Using Parietaria alsinifolia Extracts and Evaluation of Biological Applications
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Abstract The current research was conducted to synthesize Parietaria alsinifolia-mediated iron oxide nanoparticles (P.A@FeONPs) using the green and eco-friendly protocol....
Investigation and Characterization of Eco-Technological Synthesis of Spherical TiO2 Nanoparticles from Thalassia hemprichi and Analysis of Biomedical Properties
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Abstract In this present investigation, plant-mediated synthesis of titanium oxide (TiO2) nanoparticles was synthesized from seagrass (Thalassia hemprichi) using the hot...
