Materiales

 

Materiales

Lactate‐Depleting Nanotherapy Reprograms the Immunometabolic Microenvironment to Overcome Biofilm Tolerance in Implant‐Associated Infections
02/10/2026 - Lactate accumulation is associated with immunosuppression in implant‐associated infections (IAIs). A lactate‐depleting nanotherapy integrates immunometabolic remodeling with hypoxia‐activated...
A Multi‐Scale Machine Learning Framework for the Inverse Design of High Entropy Alloys
28/09/2026 - High‐entropy alloys offer vast potential for various applications, including electrocatalysis; however, their compositional complexity challenges conventional screening. We introduce an...
Dispersoid Refinement and Part Defect Optimization in Additively Manufactured Oxide‐Dispersion‐Strengthened Steels
27/09/2026 - The characteristics of powders for producing ODS steels through AM are summarized. The possible impacts of powder characteristics on part defects and NPs dispersion are discussed. Some methods...
Hypertemperature‐Detonated Biomimetic Semiconductor Stromal Bombs for Enhanced Immunotherapy in Pancreatic Cancer
28/09/2026 - We establish a modular ZIF‐8‐based MOF nanoplatform that integrates NIR‐responsive semiconducting polymer (PCPDTBT) nanoparticles (SPNs) with surface‐grown CuSx NCs and loaded with...
Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
27/09/2026 - As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored...
Quantitative single cell analysis of gold nanoparticle association across a mouse triple-negative breast cancer cell line and blood immune cell populations
- In biomedical research, understanding the heterogeneity in nanoparticle association among different cell populations is crucial for translating to efficacy and immune identification. Using...