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Artículo moldeado por inyección
26/11/2024
Métodos de flujo continuo para producir manosa-1-fosfato, polimorfos de manosa-1-fosfato y composiciones y usos relacionados con los mismos
28/11/2024 -
En el presente documento se proporcionan métodos de síntesis y composiciones que comprenden un isómero alfa de manosa-1-fosfato (M1P). Por ejemplo, dichos métodos emplean técnicas de química...
METHOD FOR MANUFACTURING PHARMACEUTICAL MINI-TABLETS
28/11/2024 -
A method for manufacturing pharmaceutical mini-tablets with a low dosage and high content of uniformity by employing drop-on-demand three-dimensional printing; a printed mini-tablet manufactured...
SOLID STATE FORMS OF ENSIFENTRINE AND PROCESS FOR PREPARATION THEREOF
28/11/2024 -
The present disclosure encompasses solid state forms of Ensifentrine, in embodiments crystalline polymorphs or salts of Ensifentrine, particularly Ensifentrine ethane-1.2-disulfonate, processes...
TARGETING RNAS ASSOCIATED WITH TAUOPATHIES WITH SMALL MOLECULES
21/11/2024 -
The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers,...
TARGETED NANOCARRIER FOR WOUND HEALING, AND METHOD FOR MANUFACTURING SAME
21/11/2024 -
The present invention relates to a targeted nanocarrier for wound healing, and a method for manufacturing same and, more specifically, to: a polymer self-assembled nano-micelle-based drug delivery...
DECREASING THE INTRINSICALLY DISORDERED PROTEIN ALPHA-SYNUCLEIN'S LEVELS BY TARGETING ITS STRUCTURED MRNA WITH A RIBONUCLEASE TARGETING CHIMERA
21/11/2024 -
The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers,...
DRUG-LOADED MACROMOLECULE OF ANTIFUNGAL DRUG AND PREPARATION METHOD THEREFOR
14/11/2024 -
The present disclosure relates to a drug-loaded macromolecule of an antifungal drug and a preparation method therefor. Specifically, the compound involved in the present disclosure is a dendritic...
PYRIMIDO MACROHETEROCYCLIC COMPOUND AS WEE1-YES DUAL-TARGET INHIBITOR AND USE THEREOF
14/11/2024 -
Disclosed in the present invention for the first time is a novel pyrimido macroheterocyclic compound having a WEE1 and Yes dual-target inhibitory activity. Specifically disclosed are a compound...
Derivado de imidazopiridazina, y método de preparación del mismo, composición farmacéutica del mismo y uso del mismo
31/10/2024 -
Se provee un derivado de imidazopiridazina, y un método de preparación del mismo, una composición farmacéutica del mismo, y el uso del mismo; se proveen específicamente un compuesto como se...
Composición sólida que comprende antagonistas del receptor de bradicinina b2 solubilizados
31/10/2024 -
La invención se refiere a dispersiones sólidas para la administración oral que comprenden un antagonista del receptor de bradicinina B2 que tiene una estructura química de acuerdo con la...
TEAD CORE INHIBITORS FOR CANCER THERAPEUTICS
24/10/2024 -
The present disclosure provides compounds of the formulae herein (e.g., Formulae I and II), and salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled...
RIMEGEPANT FAST-DISSOLVING FILMS FOR ORAL ADMINISTRATION
24/10/2024 -
A pharmaceutical composition includes a therapeutically effective amount of Rimegepant or a pharmaceutically acceptable salt thereof, and at least one film forming polymer, wherein the...
Method For Producing Patient-Optimised Dosage Forms
24/10/2024 -
The present application relates to methods of personalized pharmaceutics. More specifically, the invention relates to methods for the production of pharmaceutical dosage forms, which are produced...
Contact Lens Blister Package With Double Layer Foil Component
24/10/2024 -
A blister package for a contact lens is provided that includes a body and a seal, one or both of which is made up of a double layer foil component. The double layer foil component can be a seal...
CONJUGATED POLYETHYLENEIMINE COMPOUNDS AND COMPOSITIONS, AND USES THEREOF FOR THE TREATMENT OF ATHEROSCLEROSIS, CARDIOVASCULAR, AND LUNG DISEASE
24/10/2024 -
Provided herein are lipid conjugated polyethyleneimine (PEI) compounds of Formula (I), which are useful to form delivery systems, such as lipid nanoparticles, for delivery of agents (e.g., nucleic...
RIMEGEPANT FAST-DISSOLVING FILMS FOR ORAL ADMINISTRATION
24/10/2024 -
A pharmaceutical composition includes a therapeutically effective amount of Rimegepant or a pharmaceutically acceptable salt thereof, and at least one film forming polymer, wherein the...
Catalytic method for the synthesis of mesitylene from acetone (Machine-translation by Google Translate, not legally binding)
10/11/2020 -
Catalytic method for the synthesis of mesitylene from acetone. The present invention relates to a method for the production of mesitylene (1,3,5-trimethylbenzene) from acetone in a single stage by...
Refining process of solid sodium methoxide
15/01/2021 -
The invention belongs to the technical field of preparation processes of sodium methoxide, and particularly relates to a refining process of solid sodium methoxide. The process comprises the...
