Bioplásticos
Bioplásticos
Light‐Activated Transient Unilateral Adhesive Recombinant Collagen‐Based Hydrogel for Reversible Fibrosis Induction and Full‐Cycle Management of Pancreatic Fistula
11/07/2025 -
A light‐activated, injectable recombinant collagen‐based hydrogel plug with targeted drug delivery is developed for full‐cycle management of pancreatic fistula. Featuring enzyme resistance,...
A Sprayable Hydrogel Based on Biomimetic Polypeptide‐Modified Lipid Nanoparticles for Treating Non‐Compressible Hemorrhaging (Adv. Mater. 27/2025)
10/07/2025 -
Sprayable HydrogelThis study designs a sprayable hydrogel based on polypeptide‐modified lipid nanoparticles (PLNs) to treat non‐compressible hemorrhage. Functionalized with GFOGER and GGQQLK...
High‐Speed Raman Readout of Single Polypeptides via Plasmonic Nanopores
09/07/2025 -
A label‐free method is presented for single‐protein investigation using plasmonic nanopores that enable stable, cost‐effective Raman detection of polypeptides in real time. An average of 6...
Textile Encoding Inspired by Langer Lines via Elastically Graded Embroidered Tessellations
06/07/2025 -
A standard embroidery machine can encode skin‐like directional mechanics into stretchable fabrics that, when worn, augment the wearer's skin. Zigzag stitch patterns, inspired by skin collagen...
Elucidating Mechanisms of Gelation, Fiber Assembly, and Stability of Injectable Decellularized Extracellular Matrix Biomaterials
25/06/2025 -
Fundamental materials characterization was performed on two decellularized extracellular matrix (ECM) biomaterials (ECM hydrogel and intravascularly infusible ECM) to determine the mechanism of...
Combinational Therapy of Mesenchymal Stem Cells and Metformin in Bleomycin-Induced Idiopathic Pulmonary Fibrosis in Rat Model
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Idiopathic pulmonary fibrosis (IPF) is a progressive and severe lung disease characterized by the buildup of interstitial fibrosis, where excessive collagen accumulates, leading to airway...
Mass spectrometry imaging reveals alterations in protein and N-glycan molecular signatures in endometriosis tissues
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Endometriosis is a gynecological condition characterized by the uncontrolled growth of endometrial-like tissue outside the uterine cavity. Although highly prevalent, the biological mechanisms of...
Enhanced Growth of Bone Marrow‐Derived Mesenchymal Stem Cells on the Microcarriers Tethered With Engineered Basic Fibroblast Growth Factor
11/06/2025 -
Graphical Abstract and Lay SummaryMicrocarrier‐based bioreactors were developed for efficient expansion of human mesenchymal stem cells (hMSCs) by tethering basic fibroblast growth factor (bFGF) to...
Local Recruitment of Autologous Stem Cells via a Targeting Microgel for Precise Cartilage Repair without Surgery
03/06/2025 -
An antibody‐modified hydrogel microsphere containing TGFβ affinity peptides (TRG microsphere) is designed and synthesized to precisely target multiple scattered cartilage injury sites in advanced...
Dual Strategy of Ca2+ Influx and Collagen Denaturation to Remodel the Extracellular Matrix and Amplify Sonopiezoelectric Therapy
30/05/2025 -
The narrow bandgap of noncentrosymmetric Cu3BiS3 nanospheres facilitates charge‐carrier separation under ultrasound irradiation, resulting in a favorable sonopiezoelectric response and reactive...
Green Agarose Hydrogel Implants With High Biocompatibility for Skin Repair and Regeneration in Photoaged Skin
29/05/2025 -
ABSTRACTSkin aging is a multifaceted process marked by the destruction of skin structure and the diminishment of skin function, significantly impacting both physical and mental health. Injectable...
Traceless Photopolymerization with Non‐Pulsed Red Light Enables 3D‐Printable Cell‐Laden Hydrogels
16/05/2025 -
The paper presents a red‐light‐induced polymerization process, initiated by the FDA‐approved dye methylene blue and the cytocompatible co‐initiator triethanolamine, for fabricating hydrogels....
CS/Gel/MWCNTs Conductive Scaffolds Assisted by Electrical Stimulus for Skin Tissue Engineering
15/05/2025 -
ABSTRACTHydrogel scaffolds show high potential in tissue engineering due to excellent mechanical properties and biocompatibility. However, an inherent lack of conductivity limits its application in...
Biomimetic Dynamics of Nanoscale Groove and Ridge Topography for Stem Cell Regulation
26/04/2025 -
Dynamic nanoscale groove‐ridge structures are engineered by flexibly conjugating RGD‐magnetic nanoparticles to nanogroove templates with variable groove widths at the molecular scale. Magnetic...
Biophysical‐Inspired Interpenetrated Fibrillar and Reticular Collagen Scaffold with Vascular Endothelial Cell Membrane Incorporation for Guided In Situ Spleen Tissue Regeneration
25/04/2025 -
The spleen's complex structure limits its regenerative capacity after injury, significantly impacting patient quality of life. This work develops an inducible scaffold mimicking spleen parenchyma,...
Goat Skin (Capra aegagruss Erxleben, 1777): a Promising and Sustainable Source of Collagen
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The aim of the study was to extract and characterize collagen from solid untanned skin waste from the processing of leather in a Capra aegagrus tannery. Using pepsin (SPC), 37 g of...
Berberine Ameliorates Pulmonary Fibrosis by Inactivating the Thrombospondin 2/Smad Homolog 2/3 Pathway
18/04/2025 -
BBR treatment inhibited THBS2 expression to inactivate the Smad2/3 pathway, consequently inhibiting pulmonary fibrosis by repressing the proliferation, migration, invasion, inflammation, and...
A Sprayable Hydrogel Based on Biomimetic Polypeptide‐Modified Lipid Nanoparticles for Treating Non‐Compressible Hemorrhaging
16/04/2025 -
This study develops a sprayable hydrogel based on polypeptide‐modified lipid nanoparticles (PLNs) mimicking natural hemostasis. PLNs integrate platelet adhesion peptide (GFOGER) and platelet...
Biomimetic Intrafibrillar Mineralization of Hierarchically Structured Amyloid‐Like Fibrils
07/04/2025 -
The Hierarchically Structured Amyloid‐like Fibrils (HSAF), prepared through a mechanically directed two‐step transformation of a protein nanofilm, exhibit an ordered, dynamic layered structure...
Biodegradation Studies and Material Properties of Quercetin Incorporated Soy Protein Isolate Films
07/04/2025 -
ABSTRACTThe study aims to evaluate the effects of different contents of quercetin (1%–3%) on structural and morphological characteristics of soy protein isolate (SPI) based films fabricated by the...
Unraveling the Impact of Diverse Salt Solvent Systems on the Structure and Functionality of Eggshell Membrane Proteins
07/04/2025 -
ABSTRACTThis study investigated the effects of different solvent systems on the microstructure, roughness, and secondary structure of soluble eggshell membrane proteins (SEPs). The solvent system of...
