Bioplásticos
Bioplásticos
Osteomimix: A Multidimensional Biomimetic Cascade Strategy for Bone Defect Repair
09/02/2025 -
A multidimensional biomimetic cascade strategy for bone regeneration is developed by emulating the biomineralization cascade, hierarchical structure, and biological functions of bone tissue. The...
Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition
09/02/2025 -
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by...
Tissue Mimetic Membranes for Healing Augmentation of Tendon–Bone Interface in Rotator Cuff Repair
31/01/2025 -
Here, a tissue‐mimetic membrane for functional tendon–bone interface regeneration is fabricated. During the implantation, a biomimicry and inductive microenvironment is created by the...
Osteochondral Tissue Engineering: Scaffold Materials, Fabrication Techniques and Applications
25/01/2025 -
Graphical Abstract and Lay Summary The research on osteochondal tissue engineering scaffolds is developing rapidly, offering new possibilities for osteochondral damage. This review introduces...
Leveraging Optical Anisotropy of the Morpho Butterfly Wing for Quantitative, Stain‐Free, and Contact‐Free Assessment of Biological Tissue Microstructures
15/01/2025 -
We leverage the intrinsic optical anisotropy of the Morpho butterfly wing to introduce Morpho‐Enhanced Polarized Light Microscopy (MorE‐PoL), a stain‐ and contact‐free imaging methodology...
CircZMYM2 Alleviates TGF-β1-Induced Proliferation, Migration and Activation of Fibroblasts via Targeting miR-199b-5p/KLF13 Axis
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Abstract Dysregulated circular RNAs (circRNAs) has been revealed to be involved in pulmonary fibrosis progression. Herein, this study focused on exploring the function and...
Polyproline‐Polyornithine Diblock Copolymers with Inherent Mitochondria Tropism
10/01/2025 -
This study presents the synthesis and characterization of polypeptide‐based diblock copolymers with inherent mitochondria‐targeting properties. Utilizing a scalable 2‐step polymerization...
Rationally Engineering Pro‐Proteins and Membrane‐Penetrating α‑Helical Polypeptides for Genome Editing Toward Choroidal Neovascularization Treatment
24/12/2024 -
Adenosine triphosphate‐tagged pro‐proteins are engineered to form stable nanocomplexes with guanidyl‐rich, α‐helical polypeptide and enable robust cytosolic delivery. By delivering...
Renal Clearable Chiral Manganese Oxide Supraparticles for In Vivo Detection of Metalloproteinase‐9 in Early Cancer Diagnosis
23/12/2024 -
Chiral MnO2 supraparticles as renal‐clearance biosensors for dual‐mode in vivo detection of metalloproteinase‐9 in early cancer diagnosis via circular dichroism (CD) and magnetic resonance...
A One‐Stone‐Two–Birds Strategy for Intervertebral Disc Repair: Constructing a Reductive Chelation Hydrogel to Mitigate Oxidative Stress and Promote Disc Matrix Reconstruction
23/12/2024 -
HA‐NCSN/Cu is a new type of hydrogel formed by reducing crosslinking, which shows multi‐functions such as injectable, self‐healing, reactive oxygen species clearance, photothermal properties,...
Recent Research on Chondrocyte Dedifferentiation and Insights for Regenerative Medicine
24/12/2024 -
ABSTRACTChondrocytes maintain the balance of the extracellular matrix by synthesizing glycoproteins, collagen, proteoglycans and hyaluronic acid. Chondrocyte dedifferentiation refers to a process in...
An Immunomodulatory Hydrogel Featuring Antibacterial and Reactive Oxygen Species Scavenging Properties for Treating Periodontitis in Diabetes
28/11/2024 -
An immunomodulatory hydrogel is developed to treat periodontitis in diabetes. This formulation combines chlorhexidine acetate, epigallocatechin‐3‐gallate, gelatin methacryloyl, and oxidized...
Sequence and Configuration of a Novel Bispecific Antibody Format Impacts Its Production Using Chinese Hamster Ovary (CHO) Cells
25/11/2024 -
Bispecific BYbe® format sequence and configuration impacts secretory titre. Variable fragment (Fv) sequence and placement can reduce or enhance titre. Vector development strategies that allow tuning...
Study on the Structural Changes of Boneless Chicken Claw Collagen and Its Effect on Water Retention Performance
19/11/2024 -
The purpose of this study was to explore the water retention mechanism of chicken claws by detecting the structural changes in collagen in boneless chicken claws under different expansion rates....
Propolis Extract: Weaving Antioxidant Power into Polymeric Composites Through Electrospinning
20/11/2024 -
The manufacture of composites with bioactive compounds represents a promising strategy for developing advanced materials in biomedical, food, and industrial applications. However, challenges such as...
The Effect of Hydrodynamic Cavitation on the Structural and Functional Properties of Soy Protein Isolate–Lignan/Stilbene Polyphenol Conjugates
12/11/2024 -
In this study, hydrodynamic cavitation technology was utilized to prepare conjugates of soy protein isolate (SPI) with polyphenols, including resveratrol (RA) and polydatin (PD) from the stilbene...
Differently Processed Low Doses of β-Glucan from Oat Bran Similarly Attenuate Postprandial Glycemic Response
13/11/2024 -
Incorporating β-glucan-rich oat bran (OB) can attenuate postprandial glycemic response (PPGR) in solid foods, but its effect in liquid matrices is unclear. This study investigated the...
Design of Thermo-Responsive Pervaporation Membrane Based on Hyperbranched Polyglycerols and Elastin-like Protein Conjugates
14/11/2024 -
This paper reports the development of a highly crosslinked hyper-branched polyglycerol (HPG) polymer bound to elastin-like proteins (ELPs) to create a membrane that undergoes a distinct...
Structural and Viscoelastic Properties of Bacterial Cellulose Composites: Implications for Prosthetics
18/11/2024 -
This study investigates the morphological, mechanical, and viscoelastic properties of bacterial cellulose (BC) hydrogels synthesized by the microbial consortium Medusomyces gisevii. BC gel films were...
Recent Advances in Biomaterial?Based Scaffolds for Guided Bone Tissue Engineering: Challenges and Future Directions
12/11/2024 -
ABSTRACTBone tissue engineering (BTE) has emerged as a promising approach for the regeneration and repair of bone defects caused by trauma, disease, or aging. This review provides an overview of...
Fabrication of Antibacterial and Flexible Hydrogels Based on Citric Acid Containing Tannic Acid for Wound Dressing
13/11/2024 -
ABSTRACTIn this research, a biomonomer based on hydroxyethyl methacrylate, citric acid, and polyethylene glycol (HEMA?CA?PEG) was synthesized. After confirming the reaction through 1H?NMR and FT?IR...