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Remote‐Controlled Magnetic Stimulation of Cell‐Based Bioengineered Tissues for In Situ Bone Regeneration
07/07/2025 -
Magnetic nanoparticles and magnetic fields enable the construction of 3D tissues from individual cells and their stimulation, activating signaling pathways that influence tissue function. Herein,...
In-vitro Analysis of Solanum virginianum L. Extract and Melatonin: Synergistic Induction of Apoptosis in MDA-MB-231 Breast Cancer Cells
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Solanum virginianum (Sv) herb finds widespread usage in various medical systems, notably it is a component of the traditional herbal formulation "Dashamula". Melatonin is widely...
Aramid Nanofiber Aerogels: Preparation, Modification, Composite Fabrication, and Applications
06/07/2025 -
Different forms of aramid nanofibers (ANFs) and especially aerogels from them, offer a sustainable route to high‐performance biomimetic nanocomposites. Due to the cartilage‐like architecture,...
The Combination of UPLC MS and Derivatization Method for Analysis of Purslane for Ulcerative Colitis In Vivo
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Portulaca oleracea L. (PL) has significant clinical efficacy in treating ulcerative colitis (UC), which significantly affects patientsâ daily life. However, the absorption and...
Chemical Structure-based Graph Convolutional Model for Drug-Gut Microbiota Association Prediction
08/07/2025 -
Background Despite modern changes in global attitudes toward mental illness, it is still counted as the most stigmatized illness worldwide. This negative attitude extends to medical...
Neuroprotective Potential of Human Platelet Lysate in Parkinson's Disease: Insights Into Oxidative Stress, Mitochondrial Dysfunction, Cell Death, and Reactive Gliosis in Experimental Models
04/07/2025 -
Graphical Abstract and Lay SummaryHuman platelet lysate (HPL) biotherapy promotes neuroprotection and reduces neurodegeneration in both cellular and animal models of rotenone (ROT)‐induced...
Comparative Biomechanical Evaluation of Spinal Cages Made from PCL, PEEK, and Ti6Al4V via Support‐Free Additive Manufacturing
01/07/2025 -
This study presents a topology optimization approach that incorporates overhang constraints to design self‐supporting spinal implants suitable for additive manufacturing (AM). By integrating...
Self‐Growing Scaffold for Spatial and Border Expansive Regeneration
01/07/2025 -
Self‐growing scaffolds increase both the border and the space of obsolete defects. By balancing molecular cohesion and hydrogen bonding, the growth time can be regulated within 3–7 days. Dynamic...
Renoprotective Effects of Phloretin and TUDCA via Simultaneous Inhibition of TLR4/MyD88/NF-κB and BiP/PERK/CHOP Pathways in AKI Under Diabetic Condition
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The diabetic milieu increases the chances of acute kidney injury (AKI) progression. During AKI, activation of the inflammatory response via Toll-like receptor 4 (TLR4) and endoplasmic reticulum...
Engineering exosomes for liver disease: a new insight in regenerative medicine and drug delivery
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Exosomes, nanoscale extracellular vesicles derived from endosomes, have emerged as crucial mediators of intercellular communication, significantly influencing physiological balance and disease...
Fast Determination of Protein Binding Constants and Sites to Active Flavonoids and Phenolic Acids by Affinity Capillary Electrophoresis and Fluorescence Spectroscopy
01/07/2025 -
Determination of binding ability of flavonoids/phenolic acids to HSA by affinity capillary electrophoresis and fluorescence spectroscopy.ABSTRACTThe interaction of small molecule drugs with human...
Improving Surface Quality of Titanium Electrodeposition from a Deep Eutectic Solvent with Organic and Inorganic Additives
28/06/2025 -
Herein, the electroplating of titanium from an organic solvent, ethaline, is shown. Polymer additives are shown to smooth the roughness of the film, and small molecule additives are shown to produce...
Strategic Control of Porosity and Post‐Processing in Additive Manufacturing of Metallic Bone Scaffolds
27/06/2025 -
This article reviews advancements in 3D printing of metallic bioengineered implant scaffolds. It highlights how design, material selection, and post‐processing techniques enhance biocompatibility...
Myocardium-to-cavity ratio derived from simultaneous 99mTc-PYP/201Tl dual-isotope SPECT imaging to differentially diagnose transthyretin cardiac amyloidosis
01/07/2025 -
Background Patients with thyroid eye disease may develop dysthyroid optic neuropathy (DON), which is commonly treated via orbital decompression surgery. This study aims to identify...
Enhancement of Chondrogenesis by a Microcavitary Hydrogel Coculture System Synergizing With SDF‐1α and TGF‐Β3
28/06/2025 -
ABSTRACTA favorable microenvironment is of great significance for the repair of cartilage injury. In our previous study, a coculture system was devised, integrating genetically modified chondrocytes...
Biomaterial‐Based Fibrous Implantable Probes for Tissue‐Electronics Interface
24/06/2025 -
Biomaterial‐based fibrous implantable probes exhibit flexibility, biocompatibility, and biodegradability, making them ideal for tissue–electronics interface. This review delves into their design...
Kann ein neues Cholinergikum Sturzneigung und kognitive Beeinträchtigung bessern?
24/06/2025 -
Background Struma ovarii (SO) is a specialized monodermal teratoma composed predominantly of thyroid tissue (≥ 50%) and accounts for approximately 5% of all ovarian teratomas....
Occult intertrochanteric extension of greater trochanter fractures on magnetic resonance imaging has weak interrater reliability
24/06/2025 -
Purpose We investigated the incidence and predictors of moderate-to-severe movement-evoked pain (MEP) following gastrointestinal and hepatobiliary surgery and compare the findings for...
Homogeneous “Hard‐Soft” Biphasic Bone Adhesives Promote Comminuted Fracture Healing through Interfacial Adaptation and Mechanical Property Maintenance
13/06/2025 -
For the instant and sustainable fixation of bone fragments in treating highly comminuted fractures, phase engineering is employed to construct a homogeneous hard‐soft biphasic bone adhesive (PTN)....
