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Comparative Biomechanical Evaluation of Spinal Cages Made from PCL, PEEK, and Ti6Al4V via Support‐Free Additive Manufacturing
01/07/2025 - This study presents a topology optimization approach that incorporates overhang constraints to design self‐supporting spinal implants suitable for additive manufacturing (AM). By integrating...
Self‐Growing Scaffold for Spatial and Border Expansive Regeneration
01/07/2025 - Self‐growing scaffolds increase both the border and the space of obsolete defects. By balancing molecular cohesion and hydrogen bonding, the growth time can be regulated within 3–7 days. Dynamic...
Renoprotective Effects of Phloretin and TUDCA via Simultaneous Inhibition of TLR4/MyD88/NF-κB and BiP/PERK/CHOP Pathways in AKI Under Diabetic Condition
- The diabetic milieu increases the chances of acute kidney injury (AKI) progression. During AKI, activation of the inflammatory response via Toll-like receptor 4 (TLR4) and endoplasmic reticulum...
Engineering exosomes for liver disease: a new insight in regenerative medicine and drug delivery
- Exosomes, nanoscale extracellular vesicles derived from endosomes, have emerged as crucial mediators of intercellular communication, significantly influencing physiological balance and disease...
Fast Determination of Protein Binding Constants and Sites to Active Flavonoids and Phenolic Acids by Affinity Capillary Electrophoresis and Fluorescence Spectroscopy
01/07/2025 - Determination of binding ability of flavonoids/phenolic acids to HSA by affinity capillary electrophoresis and fluorescence spectroscopy.ABSTRACTThe interaction of small molecule drugs with human...
Improving Surface Quality of Titanium Electrodeposition from a Deep Eutectic Solvent with Organic and Inorganic Additives
28/06/2025 - Herein, the electroplating of titanium from an organic solvent, ethaline, is shown. Polymer additives are shown to smooth the roughness of the film, and small molecule additives are shown to produce...
Strategic Control of Porosity and Post‐Processing in Additive Manufacturing of Metallic Bone Scaffolds
27/06/2025 - This article reviews advancements in 3D printing of metallic bioengineered implant scaffolds. It highlights how design, material selection, and post‐processing techniques enhance biocompatibility...
Myocardium-to-cavity ratio derived from simultaneous 99mTc-PYP/201Tl dual-isotope SPECT imaging to differentially diagnose transthyretin cardiac amyloidosis
01/07/2025 - Background Patients with thyroid eye disease may develop dysthyroid optic neuropathy (DON), which is commonly treated via orbital decompression surgery. This study aims to identify...
Enhancement of Chondrogenesis by a Microcavitary Hydrogel Coculture System Synergizing With SDF‐1α and TGF‐Β3
28/06/2025 - ABSTRACTA favorable microenvironment is of great significance for the repair of cartilage injury. In our previous study, a coculture system was devised, integrating genetically modified chondrocytes...
Biomaterial‐Based Fibrous Implantable Probes for Tissue‐Electronics Interface
24/06/2025 - Biomaterial‐based fibrous implantable probes exhibit flexibility, biocompatibility, and biodegradability, making them ideal for tissue–electronics interface. This review delves into their design...
Kann ein neues Cholinergikum Sturzneigung und kognitive Beeinträchtigung bessern?
24/06/2025 - Background Struma ovarii (SO) is a specialized monodermal teratoma composed predominantly of thyroid tissue (≥ 50%) and accounts for approximately 5% of all ovarian teratomas....
Occult intertrochanteric extension of greater trochanter fractures on magnetic resonance imaging has weak interrater reliability
24/06/2025 - Purpose We investigated the incidence and predictors of moderate-to-severe movement-evoked pain (MEP) following gastrointestinal and hepatobiliary surgery and compare the findings for...
Homogeneous “Hard‐Soft” Biphasic Bone Adhesives Promote Comminuted Fracture Healing through Interfacial Adaptation and Mechanical Property Maintenance
13/06/2025 - For the instant and sustainable fixation of bone fragments in treating highly comminuted fractures, phase engineering is employed to construct a homogeneous hard‐soft biphasic bone adhesive (PTN)....
Malaria: past, present, and future
17/06/2025 - Background Papillary thyroid carcinoma (PTC) comprises the vast majority of all thyroid cancers. Lymph node metastases may be present even when the primary tumor is small and...
The Effect of Mn Content on the Mechanical and Degradation Properties of Porous Zn–Li Alloy Scaffolds
11/06/2025 - Porous Zn–0.8Li–xMn scaffolds (x = 0.1, 0.4, and 0.8) are fabricated to enhance Zn‐based implant performance. Zn–0.8Li–0.8Mn exhibits a yield strength of 21.3 MPa and a degradation...
Influence of Temperature on Scratch and Wear Properties of Technical Thermoplastics: Implications for Material Selection
10/06/2025 - The share of technical thermoplastics is expected to grow further in the e‐mobility segment. In this study, a detailed temperature‐based tribological characterization of technical thermoplastics...
De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
09/06/2025 - NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they...
Carbon‐Nanotube Synergized Robust Enzymatic‐Fuel‐Cell in Gel Microneedle for Self‐Powered Monitoring and Forecasting
04/06/2025 - A gel microneedle bioelectrodes device, with the enzymatic biofuel cells‐based monitor strategy, wireless data capture and visualization model. This devices can track the physiological activities...
Local Recruitment of Autologous Stem Cells via a Targeting Microgel for Precise Cartilage Repair without Surgery
03/06/2025 - An antibody‐modified hydrogel microsphere containing TGFβ affinity peptides (TRG microsphere) is designed and synthesized to precisely target multiple scattered cartilage injury sites in advanced...