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Cellular Glycocalyx Affects Nanoparticle Access to Cell Membranes and Uptake
23/04/2025 -
The cellular glycocalyx is a dense and negatively charged layer of carbohydrates that ubiquitously coats cells. Nanoparticles must permeate through the glycocalyx to access receptors on the cell...
Optimized Biosynthetic Pathway for Nonnatural Amino Acids: An Efficient Approach for L‐2‐Aminobutyric Acid Production
23/04/2025 -
ABSTRACTL‐2‐Aminobutyric acid (L‐2‐ABA) is a nonnatural chiral α‐amino acid which is widely used in various chiral pharmaceuticals and medical intermediates. Currently, the microbial...
An Optimized Aerogel‐Based Apheresis Device for Targeted Lipid Clearance in Elderly Hyperlipidemia Patients
21/04/2025 -
This research introduces an aerogel apheresis device specifically designed for hyperlipidemia management in elderly patients. Leveraging the unique properties of aerogels, LipClean achieves selective...
Near‐Infrared Emissive CuInS2/ZnS Quantum Dot‐Embedded Polymer Scaffolds for Photon Upconversion Imaging
16/04/2025 -
CuInS₂/ZnS quantum dots (nCIS QDs) are developed via template‐assisted cation exchange, enabling photon upconversion (UC) with NIR‐I emission, a large Stokes shift (≈650 meV), and high PLQY...
Green Fabrication of Sulfonium‐Containing Bismuth Materials for High‐Sensitivity X‐Ray Detection
10/04/2025 -
[(CH3CH2)3S]6Bi8I30 and [[(CH3CH2)3S]AgBiI5 are introduced as novel X‐ray detector materials with exceptional sensitivity and low detection limits. Produced via scalable, green synthesis, they...
Study of sampling phases for body odor sampling prior to analysis by TD-GC×GC/ToFMS
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Body odor consists of a complex matrix of volatile organic compounds (VOCs), which has garnered increasing interest in fields like medicine for its potential in disease diagnosis. However, the...
Ionic Liquid and Binary Solvent Assisted Preparation of Silk Fibroin and Polyethylene Glycol Film: Structural and Mechanical Properties
11/04/2025 -
ABSTRACTSilk fibroin (SF), a biodegradable and biocompatible material with excellent mechanical properties, is widely utilized in food packaging and medical applications. However, regenerated SF is...
Next‐Generation Flexible Embolic Systems: Targeted Transarterial Chemoembolization Strategies for Hepatocellular Carcinoma
07/04/2025 -
This review charts the transformative potential of next‐generation nano‐flexible embolic agents in redefining TACE for HCC. By dissecting innovations in tunable coagulation dynamics, real‐time...
Enhanced Mechanical Properties of Injectable Chitosan–Guar Gum Hydrogel Reinforced with Bacterial Cellulose Nanofibers for Tissue Engineering Applications
01/04/2025 -
This study presents the development and characterization of injectable nanocomposite hydrogels based on N‐succinyl chitosan, oxidized guar gum, and bacterial cellulose nanofibers. Emphasizing...
Antimicrobial Nano‐Ag/Cu Composite Coatings on Pure Ti Implants by Magnetron Sputtering Following Pretreatment for Dental Applications
28/03/2025 -
In this study, nanocomposite coatings are fabricated on the surface of pure Ti implants via a multi‐step process involving sandblasting, acid etching, hydrothermal treatment, and magnetron...
Autonomous Bioelectronic Devices Based on Silk Fibroin
23/03/2025 -
This review highlights the unique autonomous features of silk fibroin (SF), including self‐healing, shape‐morphing, and biodegradability, which enable its integration into bioelectronics. Key...
Visible Periodic Piezoelectric Domains in Silk Fibroin for Neurite‐Orientated Extension
23/03/2025 -
The piezoelectric SF film with visible periodic piezoelectric domains and excellent biocompatibility is fabricated through a feasible photochemical method with silver nanoparticles as the developer...
Ultrafast Superradiant Scintillation from Isolated Weakly Confined Perovskite Nanocrystals
21/03/2025 -
Efficiency and scintillation velocity are critical for high‐energy and medical physics. These parameters, typically conflicting in conventional scintillators, are simultaneously optimized by...
Phytochemical Investigation, Antibacterial and Antioxidant Activity Determination of Leaf Extracts of Cynoglossum coeruleum (Shimgigit)
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The leaf of Cynoglossum coeruleum is traditionally used in tropical medicine for treating various ailments. This study analyzed the phytochemicals, flavonoid and phenolic content,...
Engineering Yarrowia lipolytica for Enhanced Gastrodin Production via High‐Throughput Screening and Transcriptomics‐Guided Optimization
22/03/2025 -
High‐throughput solid‐phase extraction mass spectrometry (HP‐SPE‐MS) was developed as a robust HTS method to improve gastrodin production. Comparative transcriptomic analysis identified gene...
Biodegradable Covalent Beta‐Cyclodextrin Nanocages for Acidic and Reductive‐Responsive Drug Delivery in Enhanced Tumor Therapy
24/03/2025 -
Graphical Abstract and Lay Summary The assembly process and acidity/reduction‐sensitive drug delivery mechanism of biodegradable covalent beta‐CD nanocages for tumor therapy.ABSTRACTTraditional...
Smart Polydimethylsiloxane Materials: Versatility for Electrical and Electronic Devices Applications
16/03/2025 -
PDMS materials have found widespread applications in flexible wearable devices, medical technologies, coating protection, and thermal management. The development of smart PDMS materials featuring...
Gradient‐Metasurface‐Contact Photodetector for Visible‐to‐Near‐Infrared Spin Light
16/03/2025 -
This work presents the design and functionality of a gradient‐metasurface‐contact CPL photodetector that operates at zero bias, offering a high discrimination ratio (≈1.6 ✗ 104), broadband...
Utilization of medicinal hemp: a qualitative analysis of clinicians’ perspectives in Ghana
17/03/2025 -
We provide a mathematical framework for identifying the shortest path in a maze using a Grover walk, which becomes non-unitary by introducing absorbing holes. In this study, we define the maze as...
Health worker experiences on the integration of digital health tools for HPV vaccination and cervical cancer services in Rwanda
18/03/2025 -
Heart failure (HF) is a complex and debilitating syndrome that affects millions of people worldwide. In addition to the syndrome-related functional limitations, such as exercise intolerance and...
Synthesis of New Thiazole‐Pyrazole Analogues: Molecular Modelling, Antiproliferative/Antiviral Activities, and ADME Studies
14/03/2025 -
ABSTRACTTwelve thiazole‐pyrazole analogues 4, 6, and 8 were synthesized by introducing various pyrazole systems into the core, 2‐((4‐acetylphenyl)amino)‐4‐methylthiazole (2), through many...
