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Kultur zählt, aber Struktur entscheidet
11/11/2025 -
Background Self-care behaviors are essential for managing type 2 diabetes mellitus (T2DM), even among patients receiving specialized clinical care. However, limited evidence exists...
Investigation Into the Inhibition of Ferroptosis by Praeruptorin‐A in Sepsis Based on Network Pharmacology
06/11/2025 -
Identification of the effective molecular targets of PA during sepsis using network pharmacology. PA has the potential to inhibit LPS‐induced ferroptosis in macrophages. PA exerts its inhibitory...
A Pseudo‐Mytilus Edulis Foot Protein‐Based Hydrogel Adhesive with Osteo‐Vascular‐Immune Coupling Effects for Osteoporotic Bone‐Implant Integration
05/11/2025 -
Inspired by mussel proteins, YDC‐Gel‐Zn is a smart bone glue designed for osteoporotic implants. It adheres strongly to both metal implants and bone for initial fixation. In osteoporosis's...
Bluthochdruck-Management in der Schwangerschaft und Stillzeit
07/11/2025 -
Background Birth trauma is a complex concept that encompasses experiences spanning the perinatal period, from prenatal care to delivery and postpartum care. Despite NICU parents...
Review of Polysaccharides/Proteins Combine With Metals: A New Strategy for Wound Healing Therapy
05/11/2025 -
ABSTRACTWound dressing is crucial for managing wound healing, protecting wounds from the environment, and accelerating the healing process. Recently, wound dressing is evolving from traditional to...
Collagen and Collagen Peptide From the Alosa Sapidissima Protect Against UVB‐Induced Skin Damage
05/11/2025 -
ABSTRACTUltraviolet‐B (UVB) radiation exacerbates oxidative stress, accelerating collagen degradation and skin aging. While collagen and its hydrolysates offer therapeutic potential, medical...
A CD44‐Targeted TLR7/8 Nanovaccine for Synergistic Photothermal Immunotherapy
05/11/2025 -
Graphical Abstract and Lay SummarySchematic illustration of CuS‐PEI‐HA nanovaccine loaded with R848 and its synergistic photothermal‐immunotherapeutic mechanism. CuS‐mediated photothermal...
Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications
02/11/2025 -
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various...
A bio-SPME-LC-MS/MS method for the quantitative determination of cannabinoids in plasma samples: analytical strategy for optimization of matrix modification
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Cannabis sp. has been widely used for both medicinal and recreational purposes globally. Analyzing cannabinoids and their metabolites in human plasma samples is crucial for managing acute...
Biomass and Secondary Metabolites Enhancement in Bhringraj (Eclipta alba L.) Callus Culture Through Silver Nanoparticles Elicitation
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Silver nanoparticles (AgNPs) have surfaced as a potential agent for the augmented biosynthesis of secondary metabolites in vitro plant cultures. This research examines the impact of...
Exploring the Dual Action of Bimetallic CuO–ZnO Nanoparticles: A Green Approach to Combatting Bacteria and Vector Mosquitoes
01/11/2025 -
Graphical Abstract and Lay SummaryThis study investigates the biosynthesis of nanoparticles using orange peel extract to create monometallic CuO and ZnO nanoparticles, along with bimetallic CuO–ZnO...
Tuning the Surface State and Zeta Potential of Aged CuO Nanoparticles by Additive‐Free Surface Treatments as Guided by XPS
26/10/2025 -
Aging of CuO nanoparticles (NP) involves a surface reconstruction induced by hydroxylation and concurrent organic‐O adsorption, which introduces O defects in the NP subsurface region. The defective...
Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing
25/10/2025 -
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA...
Injectable Conductive Hydrogel Patch with Spatiotemporally Tailored Asymmetric Adhesion for Myocardial Infarction Repair
21/10/2025 -
A programmable Janus hydrogel, as a variant of double‐network systems, leverages decoupled ionic‐covalent network formation for asymmetric interface construction. This strategy enables minimally...
Dual‐Heterojunctions with Reversibly Photoactivated Structure Shift Alternately Decode Photocatalytic H2 Burst and Cascade Catalytic ROS Birth to Repress Cancer
21/10/2025 -
The g‐C3N4‐based dual‐heterojunctions, i.e., N‐doped carbon nanoribbons (N‐CNB)/g‐C3N4 and core–shell‐structured Au@Pd nanoparticles/g‐C3N4, respectively, are constructed to decode...
Deep Learning for Drug–Target Interaction Prediction: A Comprehensive Review
21/10/2025 -
This review summarizes recent deep learning approaches for drug‐target interaction prediction, including DNNs, RNNs, CNNs, GNNs, and Transformer‐based architectures, highlighting their strengths,...
Bridging Research and Application: Zn‐Based Alloys as Next‐Generation Biodegradable Orthopedic Implants
17/10/2025 -
Zinc (Zn)‐based alloys have emerged as promising options for next‐generation orthopedic implants, but their clinical acceptance faces significant challenges. This review critically evaluates the...
