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Salud
Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics
07/01/2026 -
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance...
Materials and System Design for Self‐Decision Bioelectronic Systems
07/01/2026 -
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases,...
Polypharmacological Exploration of Petroselinum Crispum for Antifibrotic Therapeutics: from Herb to Hepatoprotection
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Plant-based therapeutics are of immense importance in modern drug discovery owing to their multi-targeted mechanisms and favourable safety profiles. Among these, Petroselinum crispum has...
Phytochemical Analysis of Different Plant Organs of Bauhinia kockiana Korth. and Its Antibacterial Synergistic Interaction
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The rise of antimicrobial resistance (AMR) necessitates novel natural therapeutics. Combining plant extracts offers a promising strategy to enhance antibacterial efficacy via synergistic,...
Reverse spin bias: preliminary observations of reporting bias in medical systematic reviews
09/01/2026 -
Tofua volcano (Tonga) currently exhibits persistent, open-vent activity; however, this contrasts with previous explosive, caldera-forming eruptions. To understand the relationship between these...
Cascade‐Amplified Ratiometric Fluorescent Probe for Time‐Locked Imaging Epilepsy
05/01/2026 -
Using a cascade‐amplified ratiometric imaging strategy, we developed a highly sensitive ratiometric polymeric fluorescent probe that enables real‐time and time‐locked delineation of the...
Fluoropolymer‐Mediated Delivery of a Dual TSHR/IGF1R‐Targeting CRISPR‐Cas9 System for Localized Therapy in Thyroid‐Associated Ophthalmopathy
04/01/2026 -
A fluoropolymer‐based CRISPR‐Cas9 platform, G4F7‐CRISPR, enables dual‐gene editing of TSHR and IGF1R in orbital tissues, effectively reducing adipogenesis, inflammation, and fibrosis in...
Rhodamine B-encapsulated MOF@boric acid-modified COF for adsorption and ratiometric fluorescence detection of baicalin
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Efficient adsorption and sensitive detection of baicalin (BAI) are essential for maximizing its medical value. In this work, a rhodamine B (Rb)-encapsulated metal–organic framework (MOF)@boric...
Development and Characterization of Collagen Dressings With Jatropha mutabilis Stalk Extract in the Scar Repair Process in Rodents
04/01/2026 -
ABSTRACTThe use of medicinal plant extracts in the repair of dermal wounds has been widely discussed in the literature, especially those based on collagen, due to the diverse biological activities...
Biomimetic Molecular Tweezing at Biointerfaces: A Surface‐Driven Strategy to Disrupt Globular Protein Binding While Aligning ECM for Controlled Cellular Activity
04/01/2026 -
PVA‐stearate‐coated surface that selectively suppresses globular protein adsorption while supporting collagen fibrillar assembly. The organized ECM promotes fibroblast elongation and directional...
Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production
02/01/2026 -
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both...
Ultra‐Sensitive Nanofiber‐Based Triboelectric Nanogenerator for Energy Harvesting and Self‐Powered Sensing
30/12/2025 -
A multidimensional molecular strategy optimizes the tribonegative layer by electrospinning PVDF‐HFP for dipole alignment and crystallinity, followed by 2D borophene doping to enhance conductivity...
Silk Fibroin With Enhanced Hemostatic Property by the Introduction of Carboxyl Moieties and Preservation of Micrometer Scale Fiber Architecture
31/12/2025 -
ABSTRACTIn the realm of clinical surgery, the unceasing pursuit of hemostatic materials with rapid hemostasis, excellent biocompatibility, degradability, wound‐healing promotion, and economic...
3D Printing‐Assisted Interpenetrating‐Phase Composite Implant Materials Integrating Structural‐Functional Properties
26/12/2025 -
Interpenetrating‐phase composite implant materials are fabricated by infiltrating one constituent into 3D‐printed porous scaffolds of another. After implantation, they demonstrate two potential...
Synthesis of 4-hydroxybenzoic Acid in Escherichia coli by a Modular co-culture System
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Advancements in metabolic engineering and synthetic biology have enabled microbial production of an extensive range of valuable chemicals. Traditionally, a single microbial strain is used in these...
Engineered Oligomeric Indolizine‐Fused BODIPY Fluorophores for Interventional NIR‐II Fluorescence Imaging of Acute Cardio‐Cerebrovascular Events
24/12/2025 -
Our work represents a pivotal advancement in the design of indolizine‐fused BODIPY oligomers, specifically engineered for interventional NIR‐II fluorescence imaging of acute...
A ZK-based multi-blockchain transaction layer for minimal trust base
25/12/2025 -
Background Accurate pre- and intraoperative assessment of disease extent is crucial for curative treatment of colorectal liver metastases (CRLM) and primary colorectal cancer...
Eupatorium perfoliatum Counteracts TNF-α Mediated Pathogenesis in Chikungunya Virus Infection
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Chikungunya virus (CHIKV) infection, a neglected tropical disease causes severe morbid symptoms that can be persistent and debilitating. CHIKV mediated pathogenesis is a complex combination of...
4-Phenylbutyric acid extends the gold time of uncontrolled hemorrhagic shock at high altitude by alleviating vital organ injury
19/12/2025 -
Diabetic Foot Ulcers (DFUs) are a serious complication of diabetes, often leading to chronic infections, prolonged hospitalization, and, in severe cases, amputations. A major challenge in DFU...
A Holmium Fiber Laser with Ultrashort Pulses and Intracavity Longitudinal Scanning of a Saturable Absorber
18/12/2025 -
Background Colorectal cancer (CRC) is the fourth most common and second deadliest cancer in the US. Screening is effective at reducing CRC incidence and mortality, but rates of...
From PTFE Latex to Three Dimensional‐Printed Vascular Grafts Fabricated by DLP 3D Printing
12/12/2025 -
This work reports the 3D printing of PTFE devices using a latex‐dispersion strategy. PTFE nanoparticles dispersed in a photocrosslinkable pluronic dimethacrylate resin enable DLP printing in water....
