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Exploration of Mechanisms of Keliu Pill on the Inhibition of Lymphangiogenesis in Non-small Cell Lung Cancer Based on Network Pharmacology and Experimental Validation
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Keliu Pill (KLW) is a Chinese medicine formula that has been shown to be effective in treating non-small cell lung cancer (NSCLC) patients. However, the potential molecular mechanism remains...
Recent Advances in Microinjection Molding of Polymer Materials for Biomedical Applications
16/01/2026 -
Microinjection molding enables high‐precision polymer microstructures for biomedical applications in drug delivery, biomedical implants, and microfluidics.Microinjection molding (μIM) has emerged...
Eco-Engineered Gold Nanoparticles Via Laurus Nobilis at Native pH: Toward Multifunctional Nanoformulations for in Vitro Cancer Therapy
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In this study, gold nanoparticles (AuNPs) were developed using Laurus nobilis (LN) leaf extract, and their cytotoxic and antimigratory effects were evaluated in vitro to investigate their...
Mechanistic Study of S100A8-mediated Ferroptosis in Vascular Dementia Through the JAK2/STAT3 Pathway
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Objective To explore the mechanism of S100 Calcium Binding Protein A8 (S100A8)-mediated ferroptosis in vascular dementia (VaD) via the Janus kinase 2/signal transducer and activator...
Banking fintech and corporate innovation in China’s carbon-intensive industries: evidence from different panel approaches
15/01/2026 -
This study aims to trace nomadic imprints in the sedentary settings of the Bede community through a comprehensive survey of their housing and settlement patterns. Bede are known primarily for...
Evaluation of survival and prognostic factors in cats undergoing surgery for primary non-lymphomatous hepatobiliary tumours
15/01/2026 -
The endocannabinoid system (ECS) is evolutionarily conserved and regulates key physiological processes, including sperm motility and capacitation. However, the localization and function of...
Electrochemical desulfurative borylation of thiols, disulfides, thioethers and thioacetals
15/01/2026 -
Depression is a widespread mental disorder with profound effects on both physical and psychological health. Aberrant signal transduction contributes to depression by impairing neuronal function,...
Molecular Testing for Intrahepatic Cholangiocarcinoma: What, When, How?
15/01/2026 -
Background The 2023 armed conflict in Sudan disrupted higher education and forced a sudden shift to remote learning. This transition altered students’ physical habits,...
Peptide‐Induced Ferroelectricity in Charge‐Transfer Supramolecular Materials
10/01/2026 -
Bio‐inspired supramolecular charge‐transfer amphiphiles self‐assemble into nanoribbons in water, where peptide chirality‐induced symmetry breaking generates robust ferroelectricity across...
Acupuncture Inhibits Ferroptosis to Attenuate Cerebral Ischemia-Reperfusion Injury Through FTO-Mediated m6A Modification of ACSL4
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Acupuncture, a traditional Chinese medical intervention, is extensively utilized in the management of ischemic stroke across its various stages. However, the precise mechanisms underlying its...
Food taboos and other cultural taboos in history of miscarriage: a hospital-based study from India
12/01/2026 -
Background Emotional intelligence (EI) is increasingly recognized as an essential competency in medical education, yet evidence on its determinants and its relationship with...
Advanced Scaffold‐Guided Stem Cell Therapies for Myocardial Regeneration: Integrating Biomaterials, Cell Engineering, and Smart Delivery Systems
10/01/2026 -
Graphical Abstract and Lay SummaryStem cells can be derived from various sources such as blastocysts, bone marrow, adipose tissue, umbilical cord, or the heart itself.These cells are cultured and...
Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics
07/01/2026 -
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance...
Materials and System Design for Self‐Decision Bioelectronic Systems
07/01/2026 -
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases,...
Polypharmacological Exploration of Petroselinum Crispum for Antifibrotic Therapeutics: from Herb to Hepatoprotection
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Plant-based therapeutics are of immense importance in modern drug discovery owing to their multi-targeted mechanisms and favourable safety profiles. Among these, Petroselinum crispum has...
Phytochemical Analysis of Different Plant Organs of Bauhinia kockiana Korth. and Its Antibacterial Synergistic Interaction
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The rise of antimicrobial resistance (AMR) necessitates novel natural therapeutics. Combining plant extracts offers a promising strategy to enhance antibacterial efficacy via synergistic,...
Reverse spin bias: preliminary observations of reporting bias in medical systematic reviews
09/01/2026 -
Tofua volcano (Tonga) currently exhibits persistent, open-vent activity; however, this contrasts with previous explosive, caldera-forming eruptions. To understand the relationship between these...
Cascade‐Amplified Ratiometric Fluorescent Probe for Time‐Locked Imaging Epilepsy
05/01/2026 -
Using a cascade‐amplified ratiometric imaging strategy, we developed a highly sensitive ratiometric polymeric fluorescent probe that enables real‐time and time‐locked delineation of the...
Fluoropolymer‐Mediated Delivery of a Dual TSHR/IGF1R‐Targeting CRISPR‐Cas9 System for Localized Therapy in Thyroid‐Associated Ophthalmopathy
04/01/2026 -
A fluoropolymer‐based CRISPR‐Cas9 platform, G4F7‐CRISPR, enables dual‐gene editing of TSHR and IGF1R in orbital tissues, effectively reducing adipogenesis, inflammation, and fibrosis in...
Rhodamine B-encapsulated MOF@boric acid-modified COF for adsorption and ratiometric fluorescence detection of baicalin
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Efficient adsorption and sensitive detection of baicalin (BAI) are essential for maximizing its medical value. In this work, a rhodamine B (Rb)-encapsulated metal–organic framework (MOF)@boric...
Development and Characterization of Collagen Dressings With Jatropha mutabilis Stalk Extract in the Scar Repair Process in Rodents
04/01/2026 -
ABSTRACTThe use of medicinal plant extracts in the repair of dermal wounds has been widely discussed in the literature, especially those based on collagen, due to the diverse biological activities...
