Inyección
Inyección
Multifunctional Silicon Surfaces with Enhanced Mechanical Resistance
28/06/2025 -
Structuring silicon at micro and nanoscale reduces reflectivity but increases fragility, challenging industrial optical windows. This study develops cost‐effective fabrication processes and...
Heterojunction‐Driven Stochasticity: Bi‐Heterojunction Noise‐Enhanced Negative Transconductance Transistor in Image Generation
25/06/2025 -
This work engineered a bi‐heterojunction noise‐enhanced negative transconductance (BHN‐NTC) transistor using a half‐PTCDI‐C13 layer, achieving expanded and tunable noise characteristics....
Overall Performance Improvement of Perovskite Green LEDs by CsPbBr3&Cs4PbBr6 Nanocrystals and Molecular Doping
09/06/2025 -
A co‐additive strategy regulates perovskite crystallization, enabling CsPbBr3&Cs4PbBr6 dual‐phase nanocrystals and nanoscale concave‐convex morphology with polarity tuning via molecular...
Discovery of Small Molecule PD‐L1 Inhibitors via Optimization of Solvent‐Interaction Region for Cancer Immunotherapy
09/06/2025 -
A series of small molecule PD‐L1 inhibitors was discovered via optimization of the solvent‐interaction region. GJ19 showed the most potent anti‐PD‐L1 effects with an IC50 of 32.06 nM. GJ19...
Local Recruitment of Autologous Stem Cells via a Targeting Microgel for Precise Cartilage Repair without Surgery
03/06/2025 -
An antibody‐modified hydrogel microsphere containing TGFβ affinity peptides (TRG microsphere) is designed and synthesized to precisely target multiple scattered cartilage injury sites in advanced...
High‐Efficiency Quantum Dot Permeable Electrode Light‐Emitting Triodes for Visible Light Communications and on‐Device Data Encryption
30/05/2025 -
A novel three‐terminal PeLET device vertically integrated through a permeable electrode expands additional functionality beyond conventional two‐terminal devices. the specific mechanism is...
Green Agarose Hydrogel Implants With High Biocompatibility for Skin Repair and Regeneration in Photoaged Skin
29/05/2025 -
ABSTRACTSkin aging is a multifaceted process marked by the destruction of skin structure and the diminishment of skin function, significantly impacting both physical and mental health. Injectable...
Rapid Quantitative Assessment of Residual Stress States in PLA Components Enabled by the Combination of Photoelasticity and the Hole Drilling Method
31/05/2025 -
ABSTRACTPoly(lactic acid) (PLA) is one of the most prominent biopolymers and is considered a viable alternative to petroleum‐based polymers. While it exhibits comparable properties to conventional...
Enhanced production and purification of L-asparaginase from Bacillus paralicheniformis AUMC B-516 with potent cytotoxicity against MCF-7 cell lines
22/05/2025 -
Background The long noncoding RNA, NEAT1, is recognized as a key regulator of proinflammatory gene expression; Yet, its functional role in migraine remains unexplored, despite the...
Polyanhydride‐Based Microparticles for Programmable Pulsatile Release of Diphtheria Toxoid (DT) for Single‐Injection Self‐Boosting Vaccines
15/05/2025 -
This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high...
Sicher durch die Quartalsabrechnung
20/05/2025 -
Simvastatin is one the most commonly used drugs for treatment of hypercholesterolemia but suffers from low bioavailability (about 5%) owing to poor aqueous solubility and extensive first pass...
Development, validation, and assessment of a reliable and white method for the analysis of water-based perfumes by pipette-tip micro-solid-phase extraction combined with dual detection gas chromatography
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The analysis of possible allergens, impurities, and contaminants in perfumes and the determination of their volatile fingerprints are of high importance in determining their quality. At the same...
Lipid Nanoparticles Enhance mRNA Delivery to the Central Nervous System Upon Intrathecal Injection
03/05/2025 -
This research explores lipid nanoparticles (LNPs) for enhancing mRNA delivery to the central nervous system via intrathecal injection. By chemically engineering brain‐targeting small molecules into...
Efficient Blue Perovskite LEDs via Bottom‐Up Charge Manipulation for Solution‐Processed Active‐Matrix Displays
09/04/2025 -
A bottom‐up collaborative charge manipulation strategy is developed to minimize the interfacial charge loss in blue perovskite light‐emitting diodes, leading to stable blue electroluminescence...
Carbon Dot‐Linked Hydrogel for TAMs Transform: Spatiotemporal Manipulation to Reshape Tumor Microenvironment
03/04/2025 -
The CDs crosslinked egg white hydrogel loaded with lipopolysaccharide (LPS) and CA170 (TTF‐L‐C) can realize spatiotemporal tumor‐associated macrophages (TAMs) transformation from multi‐level...
Nose‐to‐Brain Delivery of Circular RNA SCMH1‐Loaded Lipid Nanoparticles for Ischemic Stroke Therapy
27/03/2025 -
An efficient and safe circular‐RNA delivery system circSCMH1@LNP1 is developed for direct nose‐to‐brain delivery of circRNA SCMH1 to ischemic lesions. Experiments demonstrate that intranasally...
A General Strategy for Exceptionally Robust Conducting Polymer‐Based Bioelectrodes with Multimodal Capabilities Through Decoupled Charge Transport Mechanisms
12/03/2025 -
This work presents an effective strategy to address a longstanding challenge in the practical application of soft bioelectrodes: integrating excellent electrical performance, high compactness, and...
Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction
06/03/2025 -
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These...
Nanoscale Biodegradable Printing for Designed Tuneability of Vaccine Delivery Kinetics
28/02/2025 -
Spatiotemporal Controlled Release Inks of Biocompatible polyEsters (SCRIBE) is a novel 2PP resin family with sub‐micron resolution and tuneable hydrolysis. SCRIBE enables direct printing of hollow...
Lab‐in‐Cell: A Covalent Photosensitizer Reverses Hypoxia and Evokes Ferroptosis and Pyroptosis for Enhanced Anti‐Tumor Immunity
23/02/2025 -
The covalent warhead alkynamide is incorporated into an aggregation‐induced emission photosensitizer, developing a redox systems‐targeting covalent photosensitizer MBTP‐PA. It is aimed at...
Generating Self‐Adjuvated Nanofiber Vaccines by Coating Bacterial Flagella with Antigens
21/02/2025 -
Coating bacterial flagella with antigens is used as a versatile platform for developing self‐adjuvated nanofiber vaccines. The resulting flagellum‐based subunit vaccines with appealing features...
