Materiales avanzados
Materiales avanzados
Dynamic, Reconfigurable, and Hierarchical Biosynthetic Composites via Collagen Self‐Assembly within Highly Crowded Microgel Pastes
06/12/2025 -
A new approach to extracellular matrix‐mimetic, hierarchical biomaterials is presented. Soft gels composed of overpacked hydrogel microparticle arrays present a biomolecularly crowded environment...
Review of Polysaccharides/Proteins Combine With Metals: A New Strategy for Wound Healing Therapy
05/11/2025 -
ABSTRACTWound dressing is crucial for managing wound healing, protecting wounds from the environment, and accelerating the healing process. Recently, wound dressing is evolving from traditional to...
Advances in ε‐Poly‐Lysine Biosynthesis, Selection of High‐Yielding Strains and Regulatory Mechanisms
01/09/2025 -
Graphical Abstract and Lay Summaryε‐Polylysine (ε‐PL) is a natural antimicrobial peptide widely used in food preservation and pharmaceuticals, but its low‐yield and high‐cost limit...
An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide
28/08/2025 -
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by...
Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing
31/07/2025 -
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram...
Light‐Activated Transient Unilateral Adhesive Recombinant Collagen‐Based Hydrogel for Reversible Fibrosis Induction and Full‐Cycle Management of Pancreatic Fistula
11/07/2025 -
A light‐activated, injectable recombinant collagen‐based hydrogel plug with targeted drug delivery is developed for full‐cycle management of pancreatic fistula. Featuring enzyme resistance,...
Green Agarose Hydrogel Implants With High Biocompatibility for Skin Repair and Regeneration in Photoaged Skin
29/05/2025 -
ABSTRACTSkin aging is a multifaceted process marked by the destruction of skin structure and the diminishment of skin function, significantly impacting both physical and mental health. Injectable...
Dynamic GelMA/DNA Dual‐Network Hydrogels Promote Woven Bone Organoid Formation and Enhance Bone Regeneration
23/03/2025 -
A dynamic, dual‐network CGDE hydrogel, combining covalent and noncovalent crosslinking mimics the biochemical and mechanical cues of bone extracellular matrix. This viscoelastic matrix promotes 3D...
Biomimetic rhCOL17‐P334 Conjugate for Enhanced Wound Healing
23/02/2025 -
This study presents a novel bioscaffold combining recombinant human collagen XVII (rhCOL17) with porphyra‐334 (P334) to create a transparent, injectable hydrogel (GCP) for enhanced wound healing....
Osteomimix: A Multidimensional Biomimetic Cascade Strategy for Bone Defect Repair
09/02/2025 -
A multidimensional biomimetic cascade strategy for bone regeneration is developed by emulating the biomineralization cascade, hierarchical structure, and biological functions of bone tissue. The...
A One‐Stone‐Two–Birds Strategy for Intervertebral Disc Repair: Constructing a Reductive Chelation Hydrogel to Mitigate Oxidative Stress and Promote Disc Matrix Reconstruction
23/12/2024 -
HA‐NCSN/Cu is a new type of hydrogel formed by reducing crosslinking, which shows multi‐functions such as injectable, self‐healing, reactive oxygen species clearance, photothermal properties,...
Structural and Viscoelastic Properties of Bacterial Cellulose Composites: Implications for Prosthetics
18/11/2024 -
This study investigates the morphological, mechanical, and viscoelastic properties of bacterial cellulose (BC) hydrogels synthesized by the microbial consortium Medusomyces gisevii. BC gel films were...
Design and Synthesis of Dual Galectin?3 and EGFR Inhibitors Against Liver Fibrosis
06/11/2024 -
Liver fibrosis, mainly arising from chronic viral or metabolic liver diseases, is a significant global health concern. There is currently only one FDA?approved drug (Resmetirom) in the market to...
Exploring the Potential of Anthocyanins for Repairing Photoaged Skin: A Comprehensive Review
01/11/2024 -
Long-term exposure to ultraviolet (UV) rays can result in skin photoaging, which is primarily characterized by dryness, roughness, pigmentation, and a loss of elasticity. However, the clinical drugs...
In Vitro Inhibitory Mechanism of Polyphenol Extracts from Multi-Frequency Power Ultrasound-Pretreated Rose Flower Against α-Glucosidase
27/10/2024 -
This paper explored the in vitro inhibitory mechanism of polyphenol-rich rose extracts (REs) from an edible rose flower against α-glucosidase using multispectral and molecular docking...
Designing injectable dermal matrix hydrogel combined with silver nanoparticles for methicillin-resistant Staphylococcus aureus infected wounds healing
17/10/2024 -
Hydrogel-based delivery systems have now emerged as a pivotal platform for addressing chronic tissue defects, leveraging their innate capacity to suppress pathogenic infections and facilitate...
Biomineralization Process Inspired In Situ Growth of Calcium Carbonate Nanocrystals in Chitosan Hydrogels
10/10/2024 -
Biological composites such as bone, nacre, and teeth show excellent mechanical efficiency because of the incorporation of biominerals into the organic matrix at the nanoscale, leading to hierarchical...
Mechanical and Biological Characterization of Ionic and Photo-Crosslinking Effects on Gelatin-Based Hydrogel for Cartilage Tissue Engineering Applications
27/09/2024 -
Articular cartilage degeneration poses a significant public health challenge; techniques such as 3D bioprinting are being explored for its regeneration in vitro. Gelatin-based hydrogels represent one...
Embedding Biomimetic Vascular Networks via Coaxial Sacrificial Writing into Functional Tissue
02/08/2024 -
Coaxial sacrificial writing into functional tissues (co?SWIFT) is used to embed biomimetic vascular networks into densely cellular matrices. These coaxially printed and perfusable hierarchical,...
In Situ Triggered Self?Contraction Bioactive Microgel Assembly Accelerates Diabetic Skin Wound Healing by Activating Mechanotransduction and Biochemical Pathway
23/07/2024 -
SMART?EXO, a self?contraction bioactive core–shell microgel dressing with robust tissue?adhesion, enhances diabetic wound healing by enabling tunable contraction, activating mechanotransduction,...
Natural and Synthetic Polymers for Biomedical and Environmental Applications
20/04/2024 -
Natural and synthetic polymers are a versatile platform for developing biomaterials in the biomedical and environmental fields. Natural polymers are organic compounds that are found in nature. The...
