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Artículos Técnicos

23/10/2014 - Synthesis of the antimalarial API artemether in a flow reactor

19/10/2014 - Synthesis of Internal Alkynes by Pd(PPh3)4/TMEDA‐Catalyzed Kumada Cross‐Coupling of Alkynyl Halides with Grignard Reagents (pages 6769–6773)

19/10/2014 - Discovery of potent and selective GIRK1/2 modulators via "˜molecular switches' within a series of 1-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)ureas

05/10/2014 - Synthesis of a novel universal opioid receptor agonist with the 1,3,5-trioxazatriquinane skeleton and its pharmacologies

28/09/2014 - A status review on the medicinal properties of essential oils

25/09/2014 - New Gold(I) Organometallic Compounds with Biological Activity in Cancer Cells (page 4410)

24/09/2014 - AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: Identification, SAR and pharmacological characterization

24/09/2014 - Insulin receptor antibody‐iduronate 2‐sulfatase fusion protein: Pharmacokinetics, anti‐drug antibody, and safety pharmacology in Rhesus monkeys (pages 2317–2325)

21/09/2014 - Small Molecules as Exemplars of Emergent Properties and Diversification into the ‘Adjacent Possible’ (pages 1309–1329)

21/09/2014 - Chemical Constituents of Plants from the Genus Paris (pages 1277–1297)

18/09/2014 - A metal free, eco-friendly protocol for the synthesis of 2,3-dihydro-1H-perimidines using commercially available Amberlyst 15 as a catalyst

18/09/2014 - Prediction of the crystal structures of axitinib, a polymorphic pharmaceutical molecule

18/09/2014 - Design, synthesis and pharmacological evaluation of 2-(thiazol-2-amino)-4-arylaminopyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors

18/09/2014 - Discovery of small molecular inhibitors targeting HIV-1 gp120?CD4 interaction drived from BMS-378806

16/09/2014 - Synthesis and pharmacological evaluation of optically pure, novel carbonyl guanidine derivatives as dual 5-HT2B and 5-HT7 receptor antagonists

16/09/2014 - Pharmacological characterization of actin-binding (?)-Doliculide

16/09/2014 - Synthesis and Evaluation of Antimalarial Properties of Novel 4‐Aminoquinoline Hybrid Compounds (pages 462–472)

16/09/2014 - Identification of Novel Inhibitors of Daboia russelli Phospholipase A2 Using the Combined Pharmacophore Modeling Approach (pages 379–392)

16/09/2014 - Design, synthesis and pharmacological evaluation of chalcone derivatives as acetylcholinesterase inhibitors

11/09/2014 - ASK1 pharmacophore model derived from diverse classes of inhibitors

Artículos Técnicos: 646 - Nº Páginas 33
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